QuickView for Magnesium salicylate (compound)

Summary
General Info

PubChem

PubChem Compound 5282387

Name:	Magnesium Salicylate
PubChem Compound ID:	5282387
Molecular formula:	C₁₄H₁₈MgO₁₀
Molecular weight:	370.592 g/mol
Synonyms:	Magan (TN); Magnesium salicylate (USP); 18917-95-8; Magan; D00827; Magnesium salicylate; Magnesium salicylate tetrahydrate

DrugBank

Identification

Name:	Magnesium Salicylate
Name (isomeric):	DB01397
Drug Type:	small molecule

Pharmacology

Indication:	Magnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain
Mechanism of Action:	Most NSAIDs act as nonselective inhibitors of the enzyme cyclooxygenase (COX), inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. COX catalyzes the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (amon... show more » Most NSAIDs act as nonselective inhibitors of the enzyme cyclooxygenase (COX), inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. COX catalyzes the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (among other things) as messenger molecules in the process of inflammation. show less «

Indication:

Magnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain

Mechanism of Action:

Most NSAIDs act as nonselective inhibitors of the enzyme cyclooxygenase (COX), inhibiting both the cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) isoenzymes. COX catalyzes the formation of prostaglandins and thromboxane from arachidonic acid (itself derived from the cellular phospholipid bilayer by phospholipase A2). Prostaglandins act (amon...
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Interactions

Drug interaction:

Quinidine	The antacid increases the effect of quinidine
Dexamethasone	The corticosteroid, dexamethasone, may decrease the effect of magnesium salicylate.
Gemifloxacin	Formation of non-absorbable complexes
Gliclazide	The salicylate, magnesium salicylate, increases the effect of the sulfonylurea, gliclazide.
Tetracycline	Formation of non-absorbable complexes

Targets

Prostaglandin G/H synthase 2

Prostaglandin G/H synthase 1

Carriers

Serum albumin